[ Acetoacetic acid[ Acetoacetic acid ] One of the three ketone bodies produced during the metabolic state of ketosis or ketoacidosis.... More ]
One of the three ketone bodies[ Ketone Bodies ] The three water-soluble molecules, acetoacetic acid, beta-hydroxybutyric acid and acetone, that are produced during the metabolic state of ketosis. Ketone bodies are an important source of energy for the brain and heart during fasting or strenuous exercise. They are converted into acetyl-CoA which then enter the Krebs_cycle to produce ATP. The brain also converts acetyl-CoA into... More produced during the metabolic state of ketosis[ Ketosis ] A metabolic state of ketogenesis, where the liver produces ketone bodies as a supplementary energy source. It is characterised by blood concentrations of ketone bodies over 0.5 millimolar, and low levels of insulin and blood glucose, usually triggered by fasting or a dietary shortage of carbohydrates. Compare: Ketoacidosis... More or ketoacidosis[ Ketoacidosis ] A pathological state marked by extreme state of metabolic ketosis. It decreases the pH of the blood which interferes with respiration by preventing haemoglobin from binding with oxygen, which can result in coma or death due to oxygen starvation. Diabetic ketoacidosis (DKA) occurs in type 1 diabetics when the liver overproduces ketone bodies in response to a... More.
